I was making my best attempt at running a software installer of questionable origin only to receive this error.
Runtime Error (at - 1:0): Cannot Import dll:C:\users\xxx\Temp\is-00IEG.tmp\isskin.dll
After digging around the glorious Interwebs I found an old post on WINEHQ with the same error. The answer to the problem was
winetricks vcrun6sp6 mfc42
After installing the above 2 dll's the installer worked and all was well.